Complete blood count and some cytokines levels for COVID- 19 in diabetic patients

Agharid A. Al-Rasheed¹, Mohammed A. Mustafa², Marwa T. Ahmed³

 ¹Department of Microbiology, College of Veterinary Medicine, Tikrit University, Iraq

² Department of Medical Laboratory Techniques, College of Technology, University of Imam Jafar Al-Sadiq

³Department of Microbiology, College of Medicine, University of Tikrit, Iraq

*Corresponding author: agharidalrasheed@tu.edu.iq

Received:  May 12, 2022/ Revised: June 19, 2022 / Accepted: June 22, 2022

Abstract

Coronavirus disease (COVID-19) is now a worldwide pandemic. The researchers are trying to find more about this virus in terms of diagnosis and management. Many researchers reported that the routine complete blood count is one of the main analyses to be performed for the patients as part of the confirmation test for the disease. We aim to find more about the complete blood count (CBC) of patients infected with COVID-19 and to see whether the results would show any significant differences regarding age and gender.  A group of 95 diabetic patients with confirmed COVID-19 was admitted to the Salah El- Deen Hospital in Tikrit City, Iraq. The cases were collected and analyzed from January to December 2020. CBC analysis showed a significant difference in the values of red blood cells (RBCs), white blood cells (WBC), Platelets (PLT), and its parameters (PDW & MPV) and C-reactive protein (CRP) in diabetic patients infected with COVID-19. Cytokines levels (IL-6, IL-8, IL-10, and TNF-α) were all elevated and IL-6 is believed to be a reliable biomarker for COVID-19 detection.

Keywords   Coronavirus, COVID-19, Complete blood count, WBC, PLT, HGB, CRP, cytokines. IL-6

How to cite this article

Al-Rasheed, A. A., Mustafa, M. A. and Ahmed, M. T. (2022). Complete Blood Count and some Cytokines Levels for COVID- 19 in Diabetic Patients. Science Archives, Vol. 3 (2), 120-123. http://dx.doi.org/10.47587/SA.2021.2407

References

Association, A. D. (2020). ‘How COVID-19 Impacts People with Diabetes’.

Botha-Scheepers, S., Watt, I., Slagboom, E., de Craen, A. J., Meulenbelt, I., Rosendaal, F. R. & Kloppenburg, M. (2008). Innate production of tumour necrosis factor α and interleukin 10 is associated with radiological progression of knee osteoarthritis. Annals of the rheumatic diseases, 67(8), 1165-1169.

CDC, P. (2020) ‘Cases in the US https://www. cdc. gov/coronavirus/2019-ncov/cases-updates/cases-in-us. html’. Accessed.

Chen, X., Zhao, B., Qu, Y., Chen, Y., Xiong, J., Feng, Y. & Li, F. (2020). Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients. Clinical infectious diseases.

Guan, W. J., Ni, Z. Y., Hu, Y., Liang, W. H., Ou, C. Q., He, J. X. & Zhong, N. S. (2020). Clinical characteristics of coronavirus disease 2019 in China. New England journal of medicine, 382(18), 1708-1720.

Mustafa, M. A., & AL-Samarraie, M. Q. (2020). Secondary menopause and its relationship to hormonal levels among women at Salah Al-Din Hospital. European Journal of Molecular & Clinical Medicine, 7(09), 96-104.

Mustafa, M. A., AL-Samarraie, M. Q., & Ahmed, M. T. (2020). Molecular techniques of viral diagnosis. Science Archives, 1(3), 89-92.

Ng, K. E., & Rickard, J. P. (2020). The effect of COVID-19 on patients with diabetes. US Pharm, 45(11), 9-12.

Razzaghi, H. et al. (2020) ‘Estimated County-Level Prevalence of Selected Underlying Medical Conditions Associated with Increased Risk for Severe COVID-19 Illness — United States, 2018’, MMWR. Morbidity and Mortality Weekly Report, 69(29). doi: 10.15585/mmwr.mm6929a1

Wang, H., Luo, S., Shen, Y., Li, M., Zhang, Z., Dong, Y. & Hu, D. (2020). Multiple enzyme release, inflammation storm and hypercoagulability are prominent indicators for disease progression in COVID-19: a multi-centered, correlation study with CT imaging score.

Welsh, P., Murray, H. M., Ford, I., Trompet, S., de Craen, A. J., Jukema, J. W. & PROSPER Study Group. (2011). Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, thrombosis, and vascular biology, 31(10), 2338-2344.

Xia, C., Liu, Y., Chen, Z., & Zheng, M. (2015). Involvement of interleukin 6 in hepatitis B viral infection. Cellular Physiology and Biochemistry, 37(2), 677-686.

Zhong, J. (2020). ‘The immunology of COVID-19: is immune modulation an option for treatment?’. The Lancet Rheumatology. Lancet Publishing Group, pp. e428–e436. doi: 10.1016/S2665-9913(20)30120-X.

Licence                  Article Metadata

This work is licensed under a Creative Commons Attribution 4.0 International License.