Lamiaa Mohammed Jassim¹✉, Sura Mouaid Abbass², Ayat majeed zeadan², Rawaa Saadi Selman²
¹Microbiology Laboratory, Al-fadhael Secondary School
²Medical Laboratory Technique Department, Alnukhba University Collage, Baghdad, Iraq
Received: Feb 22, 2023/ Revised: Mar 21, 2023/ Accepted: Mar 30, 2023
(✉) Corresponding Author: lamiaamasterbiology@gmail.com
Abstract
Stenotrophomonas maltophilia is a common microorganism that is linked to opportunistic illnesses. Growing prevalence and severity of sickness were seen in immunocompromised hosts, especially opportunistic bloodstream infections and pneumonia syndromes. The present research involved studies published from PubMed and Google Scholar databases resulting in 100 open-access articles. A systematic review and meta-analysis were performed to study virulence factors of S. maltophilia as well as genes that play a role in bacteria’s resistance to antibiotics that contribute to increased bacterial pathogenicity. The result showed virulence factors of S. maltophilia include (fimbrial operon , extracellular enzymes), biofilm production, antibiotic-resistant gene having the main roles in bacteria pathogenicity. In conclusion: S. maltophilia have a significant death rate, and the risk factors for mortality depend on the early diagnostic state and patient population. Additionally, to reduce bacteria’s resistance to antibiotics, appropriate treatments must be used to treat and control infection.
Keywords: Stenotrophomonas maltophilia, Virulence factors, Antibiotic resistance gene
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How to cite this article
Jassim, L.M., Abbass, S.M. Zeadan, A.M. and Selman, R.S. (2022). Evaluation of virulence factors in Stenotrophomonas maltophilia: a systematic review. Science Archives, Vol. 4(1), 59-66. https://doi.org/10.47587/SA.2023.4110
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