University of Sumer, Baghdad, Iraq
saadg.hussein@gmail.com, S.hussien@uos.edu.iq
Article History: Received: Nov 19, 2020 / Revised: Dec 22, 2020/ Accepted: Dec 25, 2020
Abstract
The goal of our project was to evaluate hypothyroidism and its effect on sex hormones for patients’ women. One hundred patients had visited the endocrine clinic in Thi- Qar province, Iraq. The results showed the effect of hyperactive or unusually energetic TSH was usually caused hypoactive of FT- 4 and FT- 3 that affect on sex hormones levels and produced a significant P < 0.05 for different sex hormones, such as Prolactin, LH, FSH, Progesterone and FT- 4 a significant difference was shown only in Prolactin, TSH hormones levels which are generally secreted from the anterior pituitary gland. TSH (Thyroid Stimulating Hormone) and prolactin hormones were playing and contribute to the development of the cystic ovaries in women. This study measures the level of prolactin, TSH, FT- 4, and FT- 3 in ladies suffering from polycystic ovaries, while the hyperactive TSH causes hypoactive of FT- 3 and FT- 4. But from this study showed prolactin causes cystic ovaries P < 0.05 there is a significant overlap between hypothyroidism, prolactin, and cystic ovaries.
Keywords TSH, T- 3, T- 4, Prolactin, Cystic Ovaries and Patients
How to cite this article
Hussein, S. G., (2020). Impact of hypothyroidism on sex hormones level, cystic ovaries and infertility in women. Science Archives, 1 (3), 194-196. http://dx.doi.org/10.47587/SA.2020.1319
Crossref DOI
http://dx.doi.org/10.47587/SA.2020.1319
References
Alzahra Ibrahim Abdulmajeed,” Effect of thyroid disorder in polycystic ovarian syndrome in the women of Diyala province, ” Ibn Al- Haitham journal for pure and app.sci.vol.31(1) 2018.
Demura, R., Ono, M., Demura, H., Shizume, K., & Oouch, H. (1982). Prolactin directly inhibits basal as well as gonadotropin-stimulated secretion of progesterone and 17β-estradiol in the human ovary. The Journal of Clinical Endocrinology & Metabolism, 54(6), 1246-1250.
Elslimani, F. A., Elhasi, M., And Elmhdwi, M. F. “the relation between hypothyroidism and polycystic ovary syndrome”, j pharm applchem, Vol. 2, pp. 197-200, 2016.
Hamoda, H., Khalaf, Y., & Carroll, P. (2012). Hyperprolactinaemia and female reproductive function: what does the evidence say?. The Obstetrician & Gynaecologist, 14(2), 81-86.
Jelodar, G., & Askari, K. (2012). Effect of Vitex agnus-castus fruits hydroalcoholic extract on sex hormones in rat with induced polycystic ovary syndrome (PCOS). Physiology and Pharmacology, 16(1), 62-69.
Krassas, G. E. (2000). Thyroid disease and female reproduction. Fertility and sterility, 74(6), 1063-1070.
Krassas, G. E., Poppe, K., & Glinoer, D. (2010). Thyroid function and human reproductive health. Endocrine reviews, 31(5), 702-755.
Nanda, S. S., Dash, S., Behera, A., & Mishra, B. (2014). Thyroid profile in polycystic ovarian syndrome. Journal of Evolution of Medical and Dental Sciences, 3(37), 9594-9601.
Saran, S., Gupta, B. S., Philip, R., Singh, K. S., Bende, S. A., Agroiya, P., & Agrawal, P. (2016). Effect of hypothyroidism on female reproductive hormones. Indian Journal of Endocrinology and Metabolism, 20(1), 108.
SAS, “Statistical Analysis System, User’s Guide. Statistical”, Version 9.1th ed. SAS, Vol. Inst. Inc. Cary. N.C. USA, 2012
Shirsath, A., Aundhakar, N., & Kamble, P. (2015). Does the thyroid hormonal levels alter in polycystic ovarian disease? A comparative cross sectional study. Indian Journal of Basic and Applied Medical Research, 4(3), 265-271.
Tortora, G. J., & Derrickson, B. H. (2018). Principles of anatomy and physiology. John Wiley & Sons.
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