Raghad Hazem Alabbasy
Department of Pathological Analysis, College of Applied Sciences, University of Samarra, Iraq
*Corresponding author: raghad.h@uosamarra.edu.iq
Received: May 14, 2022/ Revised: June 18, 2022 / Accepted: June 21, 2022
Abstract
This study was carried out to investigate the therapeutic effect of the water extract of the Hibiscus sabdariffa lin and its effect as an antioxidant on some physiological variables in male white mice exposed to oxidative stress induced by ethanol. Twenty adult white male mice aged 2-3 months were used with weights ranging from 20-30 g, divided into four groups of 5 rats per group. The groups were as follows: control group (G1), second group (G2) was given 5% of ethanol and the third group (G3) was given ethanol and water extract for Hibiscus sabdariffa lin at a concentration of 10%, and (G4) group was given ethanol and water extract of Hibiscus sabdariffa lin at a concentration of 20.
Keywords Therapeutic, Hibiscus sabdariffa lin, Male White Mice, Oxidative Stress
References
Al Asmari, A., Al Shahrani, H., Al Masri, N., Al Faraidi, A., Elfaki, I., & Arshaduddin, M. (2016). Vanillin abrogates ethanol induced gastric injury in rats via modulation of gastric secretion, oxidative stress and inflammation. Toxicology reports, 3, 105-113.
Anderson, J. W. (2003). Whole grains protect against atherosclerotic cardiovascular disease. Proceedings of the Nutrition Society, 62(1), 135-142.
Arai, Y., Watanabe, S., Kimira, M., Shimoi, K., Mochizuki, R., & Kinae, N. (2000). Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration. The Journal of nutrition, 130(9), 2243-2250.
Babu, T. S., Akhtar, T. A., Lampi, M. A., Tripuranthakam, S., Dixon, D. G., & Greenberg, B. M. (2003). Similar stress responses are elicited by copper and ultraviolet radiation in the aquatic plant Lemna gibba: implication of reactive oxygen species as common signals. Plant and Cell Physiology, 44(12), 1320-1329.
Brüske-Hohlfeld, I., Rosario, A. S., Wölke, G., Heinrich, J., Kreuzer, M., Kreienbrock, L., & Wichmann, H. E. (2006). Lung cancer risk among former uranium miners of the WISMUT Company in Germany. Health physics, 90(3), 208-216.
Chen, H. Y., Lin, Y. C., & Hsieh, C. L. (2007). Evaluation of antioxidant activity of aqueous extract of some selected nutraceutical herbs. Food chemistry, 104(4), 1418-1424.
Kim, J. K., So, H., Youn, M. J., Kim, H. J., Kim, Y., Park, C. & Park, R. (2007). Hibiscus sabdariffa L. Water extract inhibits the adipocyte differentiation through the PI3-K and MAPK pathway. Journal of ethnopharmacology, 114(2), 260-267.
Mensah, J. K., & Golomeke, D. (2015). Antioxidant and antimicrobial activities of the extracts of the Calyx of Hibiscus Sabdariffa Linn. Current Science Perspectives, 1(2), 69-76.
Prince, M., Ferri, C. P., Acosta, D., Albanese, E., Arizaga, R., Dewey, M. & Uwakwe, R. (2007). The protocols for the 10/66 dementia research group population-based research programme. BMC public health, 7(1), 1-18.
Pujiastuti, E. (2016). Pengaruh fraksi etil asetat kulit batang juwet (Syzygium cumini L.) Terhadap penurunan kadar glukosa darah pada tikus diabetes mellitus tipe II resistensi insulin. Jurnal Keperawatan dan Kesehatan Masyarakat Cendekia Utama, 5(1).
Sabu, M. C., & Kuttan, R. (2002). Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. Journal of ethnopharmacology, 81(2), 155-160.
Sathiyanarayanan, L. & Arulmozhi, S. (2007). Mucuna pruriens Linn.-A comprehensive review. Pharmacognosy Reviews, 1(1), 157-161.
Shi, L. J., Han, H. L., & Zhang, S. X. (2008). Virus Location and Lymphocyte Apoptosis in Lymph Nodes of Piglets Infected with PCV-2. Agricultural Sciences in China, 7(4), 507-512.
Szekanecz, Z., Kerekes, G., Der, H., Sandor, Z., Szabo, Z., Vegvari, A. & Soltesz, P. (2007). Accelerated atherosclerosis in rheumatoid arthritis. Annals of the New York Academy of Sciences, 1108(1), 349-358.
How to cite this article
Alabbasy, R. H. (2022). Therapeutic Effect of Hibiscus sabdariffa lin on Some Physiological variables in Male White Mice Exposed to Oxidative Stress. Science Archives, Vol. 3 (2), 139-42. http://dx.doi.org/10.47587/SA.2022.3210
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